WebThe GCH1 gene provides instructions for making an enzyme called GTP cyclohydrolase 1. This enzyme is involved in the first of three steps in the production of a molecule called tetrahydrobiopterin (BH4). Other enzymes help carry out the second and third steps in this process. Tetrahydrobiopterin plays a critical role in processing several ... WebMar 14, 2005 · Sequence analysis revealed that QueF is homologous to the GTP …
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WebJun 4, 1993 · Guanosine triphosphate (GTP) cyclohydrolase I, the rate-limiting enzyme in the biosynthesis of tetrahydrobiopterin (BH 4), is subject to feedback inhibition by BH 4, a cofactor for phenylalanine hydroxylase.Inhibition was found to depend specifically on BH 4 and the presence of another protein (p35). The inhibition occurred through BH 4 … WebMay 4, 2016 · (GenBank) GTP cyclohydrolase I. KO: K01495 : GTP cyclohydrolase IA [EC:3.5.4.16] Organism: ecj Escherichia coli K-12 W3110. Pathway: ecj00790 : Folate biosynthesis: ecj01100 : Metabolic pathways: ... JW2140 (folE) Enzymes [BR:ecj01000] 3. Hydrolases 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds haja le top
6210693 - Gene ResultfolE GTP cyclohydrolase I FolE []
WebDec 8, 2006 · GTP cyclohydrolase I (GCYH-I) is the first enzyme of the de novo tetrahydrofolate biosynthetic pathway present in bacteria, fungi, and plants, and encoded in Escherichia coli by the folE gene. It is also the first enzyme of the biopterin (BH4) pathway in Homo sapiens, where it is encoded by a homologous folE gene. A homology-based … Web(GenBank) GTP cyclohydrolase I FolE. KO: K01495 : GTP cyclohydrolase IA [EC:3.5.4.16] Organism: lfl Luteibacter flocculans. Pathway: lfl00790 : Folate biosynthesis: lfl01100 : Metabolic pathways: lfl01240 : Biosynthesis of cofactors: Brite: KEGG Orthology (KO) [BR:lfl00001] 09100 Metabolism 09108 Metabolism of cofactors and vitamins haja louvor