WebApr 5, 2024 · Drug-coated balloons (DCBs) have become an established therapy for the treatment of above-the-knee peripheral artery disease. The paclitaxel DCB has shown clinical benefit in terms of patency and ... WebIn this review we first outline the development of paclitaxel-coated balloons to then provide an overview of the preclinical results obtained with different paclitaxel-coated balloons and finally compare these with the outcome in patients. The article concludes with a short outlook on initial results with a zotarolimus-coated angioplasty balloon.
Mortality and Paclitaxel-Coated Devices Circulation
WebIntroduction: Paclitaxel is a microtubule-stabilizing drug used to treat several types of cancer, including ovarian and breast cancer. Because of its antiproliferative effect on vascular smooth muscle cells, balloons and stents are coated with paclitaxel for use in coronary revascularization and prevention of in-stent restenosis (ISR). WebMay 6, 2024 · Paclitaxel-coated angioplasty balloons and paclitaxel-eluting stents have demonstrated effectiveness in treating femoropopliteal peripheral artery disease (PAD) by reducing reintervention through 5-year follow-up. 1,2 However, an aggregate-level meta-analysis 3 raised concerns of increased all-cause late mortality, manifested ≥2 years after ... hellsing art
Trial of a Paclitaxel-Coated Balloon for Femoropopliteal Artery Disease
WebThe drug-coated balloon carries a paclitaxel dose of 3.5 μg per square millimeter with a urea excipient. It is a 0.035-in. guidewire-compatible device, and the sizes used in the trial included ... WebDedicated to Transparency. There have been concerns surrounding the safety of paclitaxel in therapies to treat peripheral artery disease (PAD). Medtronic is dedicated to data … WebThe Jetstream Atherectomy followed by Paclitaxel-Coated Balloons versus Balloon Angioplasty Followed by Paclitaxel-Coated Balloons (JET-RANGER Study) (NCT03206762) is a randomized trial of Jetstream atherectomy (JET) plus paclitaxel coated balloon (PCB) versus balloon angioplasty (PTA) plus PCB of the femoropopliteal artery (FP). hellsing assistir online