Thr766
WebThe docking result of the EGFR inhibitors with EGFR. (a) The binding site of compound 27 with EGFR is Thr766. (b) The binding site of compound 28 with EGFR is Met769. (c) The binding site of compound 30 with EGFR is Met769. (d) The binding site of compound 31 with EGFR is Met769. (e) The binding site of compound 32 with EGFR is Met769. (f) The … Webby side chains of residues Met742, Cys751, Leu764, Thr766, Thr830, Phe832, and part of Lys721. ATP does not interact with residues within this pocket, but the pocket is important
Thr766
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WebAnti-phospho AKAP-12/Gravin Antibody (Thr766) serum, from rabbit; Synonyms: A-kinase anchor protein 12, Thr766 phosphorylated, A-kinase anchor protein 250 kDa, Thr766 phosphorylated, AKAP-12, Thr766 phosphorylated, AKAP 250, Thr766 phosphorylated, Gravin, Thr766 phosphorylated, Myasthenia gravis autoantigen, Thr766 phosphorylate; … WebNM_000088.4(COL1A1):c.2298T>C (p.Thr766=) AND multiple conditions Clinical significance: Benign (Last evaluated: Aug 9, 2024) Review status: 1 star out of maximum …
WebAnti-phospho AKAP-12/Gravin Antibody (Thr766) serum, from rabbit; Synonyms: A-kinase anchor protein 12, Thr766 phosphorylated, A-kinase anchor protein 250 kDa, Thr766 … WebJul 5, 2024 · Cys773, Met769, Thr766, Lys721, Thr830, Gly772 and Leu694 : The second parameter to look at is the Gibbs free energy value. Based on Eleftheriou et al.(2024), a compound can stably interact with its receptors if it has a value of Gibbs free energy lower than 5.5 kcal/mol. Therefore, the compound ...
WebNM_000088.4(COL1A1):c.2298T>C (p.Thr766=) AND multiple conditions Clinical significance: Benign (Last evaluated: Aug 9, 2024) Review status: 1 star out of maximum of 4 stars WebApr 11, 2024 · Mass spectrometry is the most frequently used technique for proteomic study (Dutta et al., 2024, Chanda et al., 2024), especially high-resolution mass spectrometry …
WebAKAP-12/Gravin is phosphorylated on Thr766 in mitotic cells, T766A phosphosite mutant is unable to interact with Plk1 and negatively impacts cell proliferation. AKAP-12/Gravin is …
WebAKAP-12/Gravin is phosphorylated on Thr766 in mitotic cells, T766A phosphosite mutant is unable to interact with Plk1 and negatively impacts cell proliferation. AKAP-12/Gravin is … lightwire theater ticketsWebApr 25, 2003 · Mutation of Thr-315 in Abl to isoleucine by a C to T single nucleotide change (ACC to ATC) rendered BCR-ABL kinase activity resistant to STI571 in advanced CML patients ().The molecular basis for these results was provided by the Abl tyrosine kinase crystal structure, which identified Thr-315 in Abl as a key determinant for STI571 binding (). light wiring and switchWebMar 1, 2016 · ABSTRACT Objective: The objective of the research is to design a new hydroxy xanthone derivative has anticancer activity using quantitative structure-activity … lightwishWebNational Center for Biotechnology Information lightwise bulbsWebMay 1, 2024 · The discovery of specific cancer treatments was based on virtual techniques like molecular docking. By using in silico virtual screening techniques, it is possible to target and process multiple molecules involved in the signaling pathway. The ErbB family of receptor tyrosine kinases, or RTKs, is one of oncology's primary targets and is crucial for … light wisconsinWebJun 25, 2024 · All RNA viruses encode the RNA-dependent RNA polymerase (RdRp) which replicates and transcribes viral RNA. This essential viral enzyme does not exist in mammalian cells, thus presents a main target for the development of antiviral drugs with potential pan-antiviral activity. In this study, we take advantage of the structurally … light witch tarot shop youtubeWebDocking experiments showed that trans-cinnamaldehyde was proficiently fitted into the inner grove of the active site of EGFR by making close inter-atomic contacts with the key catalytic residues Val702, Ala719, Lys721, Leu764, Thr766 and Leu820 and with inhibition constant Ki … light wispy curtain bangs